Titre du document / Document title

Incorporation of stearic acid (18:0) and palmitic acid (16:0) in phospholipid molecular species studied in isolated rat liver cells

Auteur(s) / Author(s)

WOLDSETH B. ; CHRISTENSEN E. ; CHRISTOPHERSEN B. O. ;

Affiliation(s) du ou des auteurs / Author(s) Affiliation(s)

Univ. Oslo, rikshosp., inst. clin. biochemistry, 0027 Oslo, NORVEGE

Résumé / Abstract

The incorporation of [1-¹⁴C]16:0 and [1-¹⁴C]18:0 in the molecular species of PC pond PE in isolated rat liver cells was studied. More [¹⁴C]18:0 than [¹⁴C]16:0 was esterified both in PC and PE. Also the chain elongated and desaturated products (16:1, 18:0 and 18:1) were incorporated. The main molecular phospholipid species formed from [¹⁴C]18:0 were 18:0-18:2, 18:0-20:4 and 18:0-22:6. 18:0-18:0 species was not detected, independent of the substrate concentration (0.1-0.9 mM). With [¹⁴C]16:0 at low substrate concentration (0.1 mM) the dominating species are 16:0-18:2, 16:0-20:4 and 16:0-22:6. These species were detected already after 10 min

Revue / Journal Title

Biochimica et biophysica acta, L. Lipids and lipid metabolism   ISSN 0005-2760 

Source / Source

1993, vol. 1167, n^o3, pp. 296-302 (30 ref.)

Langue / Language

Anglais

Editeur / Publisher

Elsevier, Amsterdam, PAYS-BAS (1965-1998) (Revue)

Mots-clés anglais / English Keywords

Phosphatidylcholine ; Phosphatidylethanolamine ; Palmitic acid ; Stearic acid ; Molecular species ; Phospholipid ; Biosynthesis ; Hepatocyte ; Rat ; Rodentia ; Mammalia ; Vertebrata ;

Mots-clés français / French Keywords

Phosphatidylcholine ; Phosphatidyléthanolamine ; Palmitique acide ; Stéarique acide ; Espèce moléculaire ; Phospholipide ; Biosynthèse ; Hépatocyte ; Rat ; Rodentia ; Mammalia ; Vertebrata ;

Mots-clés espagnols / Spanish Keywords

Fosfatidilcolina ; Fosfatidiletanolamina ; Palmítico ácido ; Esteárico ácido ; Especie molecular ; Fosfolípido ; Biosíntesis ; Hepatocito ; Rata ; Rodentia ; Mammalia ; Vertebrata ;

Localisation / Location

INIST-CNRS, Cote INIST : 3973 G, 35400003627412.0090